Göttingen, Niedersachsen
The department of neurology has an immediate opening of a:
The research group Translational Neuroinflammation under the direction of Prof. Martin Weber focuses on understanding pathological and immunological mechanisms in the development and progression of demyelinating diseases of the central nervous system (CNS). We mainly focus on multiple sclerosis, Neuromyelitis optica spectrum disease (NMOSD) and anti-MOG antibody-associated disease.
Multiple Sclerosis (MS) is an inflammatory demyelinating disease of the CNS. For relapsing-remitting MS, huge progress has been made in the development of various disease-modifying therapies, which effectively reduce the number and the severity of new relapses as well as MRI activity.
There are a few project options available to choose from: One aim would be to test suitable candidates for the treatment of MS via animal models and in vitro analysis. For in vivo experiments, we will utilize the murine MS model experimental autoimmune encephalomyelitis (EAE) as well as the cuprizone-induced model of demyelination. For in vitro experiments, primary cell cultures of CNS-resident cells will be used. The main methods of this study will be among others flow cytometry, magnetic-activated cell sorting, ELISA, qPCR and immunohistology. Another project idea is to analyze already acquired liquor samples from patients using mass spectroscopy. It is still unknown how inflammatory demyelinating disease of the CNS develops and using this method we aim to find possible biomarkers to be used as a diagnostic marker and potential treatment criteria.
The University Medical Center Göttingen is committed to professional equality. We therefore seek to increase the proportion of under-represented genders. Applicants with disabilities and equal qualifications will be given preferential treatment.
We look forward to receiving your application by May 31 th, 2024
University Medical Center Göttingen
Klinik für Neurologie
Prof. Dr. med. Martin Weber
Stellvertretender Direktor der Klinik für Neurologie
D-37099 Göttingen
Phone: +49 (0) 551/39-67087
email
Web: https://neuropathologie.umg.eu/forschung/arbeitsgruppen-labore/ag-martinweber/
Contact person
Please send your application by May 31 th, 2024 with a cover letter (explaining your background and motivation), resume and references to both Prof. Dr. med. Martin
Weber and Dr. Sarah Dybowski.
Mr. Prof. Dr. med. Martin Weber, Stellvertretender Direktor der Klinik für Neurologie
(email)
Mrs. Dr. Sarah Dybowski (email)
Phone: +49 (0) 551/39-20489
Travel and application fees cannot be refunded or transferred.
Please send your application only via e-mail as a PDF-file.
37073 Göttingen
Niedersachsen
Deutschland